Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211998 | 1.00 | ALDH1A1 (0.38) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL9217629 | 0.95 | SLC1A3 (0.36) | ALDH1A1MEN1KMT2ANAMPTCYP3A4 | |
| SCHEMBL9219765 | 0.92 | ALDH1A1 (0.39) | ALDH1A1GAAMEN1KMT2ANAMPT | |
| SCHEMBL9211109 | 0.92 | MEN1 (0.37) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL9216670 | 0.91 | P2RX7 (0.33) | ALDH1A1GAAMEN1KMT2APTGS2 | |
| SCHEMBL9215115 | 0.91 | KEAP1 (0.39) | ALDH1A1MEN1KMT2AMAPTNAMPT | |
| SCHEMBL9212243 | 0.90 | NAMPT (0.38) | ALDH1A1MEN1KMT2ANAMPTSMN1; SMN2 | |
| SCHEMBL9218839 | 0.90 | KMT2A (0.36) | ALDH1A1GAAMEN1KMT2ANAMPT | |
| SCHEMBL9209313 | 0.88 | NAMPT (0.33) | ALDH1A1MEN1KMT2ANAMPTSLC1A3 | |
| SCHEMBL9211995 | 0.88 | GRIA2 (0.32) | ALDH1A1GAACNR2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |