Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219145 | 0.89 | PGR (0.36) | HTR6CYP19A1KMT2AGAAMEN1 | |
| SCHEMBL9215505 | 0.83 | GAA (0.38) | HTR6MAPTCYP19A1KMT2AGAA | |
| SCHEMBL9215943 | 0.79 | AVPR1B (0.35) | MAPTKMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9217225 | 0.79 | GAA (0.36) | CYP19A1KMT2AGAAMEN1PGR | |
| SCHEMBL9283967 | 0.76 | RELA (0.38) | MAPTKMT2AGAAMEN1PGR | |
| SCHEMBL9217994 | 0.76 | POLB (0.39) | CYP19A1KMT2AGAAMEN1PGR | |
| SCHEMBL9222426 | 0.75 | OXTR (0.36) | KMT2AGAAMEN1CA1CA2 | |
| SCHEMBL9218505 | 0.75 | PGR (0.31) | CYP19A1KMT2AGAAMEN1PGR | |
| SCHEMBL9220685 | 0.74 | KMT2A (0.42) | HTR6KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9211620 | 0.73 | RAPGEF3 (0.34) | KMT2AGAAMEN1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |