Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.33 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215306 | 0.89 | HTR6 (0.39) | PGRMDM2KMT2ACA1CA2 | |
| SCHEMBL9215943 | 0.89 | AVPR1B (0.35) | KMT2ACBX7CDYLALDH1A1GAA | |
| SCHEMBL9283967 | 0.86 | RELA (0.38) | PGRKMT2AALDH1A1GAAPKM | |
| SCHEMBL9217225 | 0.85 | GAA (0.36) | PGRKMT2ACYP19A1CBX7CDYL | |
| SCHEMBL9222426 | 0.81 | OXTR (0.36) | KMT2ACA1CA2CBX7CDYL | |
| SCHEMBL9218505 | 0.81 | PGR (0.31) | PGRKMT2ACYP19A1CBX7CDYL | |
| SCHEMBL9220685 | 0.81 | KMT2A (0.42) | KMT2AALDH1A1HTR6 | |
| SCHEMBL9217994 | 0.81 | POLB (0.39) | PGRKMT2ACYP19A1CBX7CDYL | |
| SCHEMBL9211620 | 0.79 | RAPGEF3 (0.34) | KMT2ACBX7CDYLALDH1A1GAA | |
| SCHEMBL6602895 | 0.79 | AVPR1B (0.35) | MDM2KMT2ACYP19A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |