Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 10/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219145 | 0.81 | PGR (0.36) | KMT2AALDH1A1HTR6 | |
| SCHEMBL9217225 | 0.78 | GAA (0.36) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9222426 | 0.76 | OXTR (0.36) | KMT2AAVPR1BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9217994 | 0.75 | POLB (0.39) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7471578 | 0.75 | AVPR1B (0.66) | AVPR1B | |
| SCHEMBL9215306 | 0.74 | HTR6 (0.39) | KMT2AALDH1A1LMNASMN1; SMN2HTR6 | |
| SCHEMBL9211620 | 0.74 | RAPGEF3 (0.34) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9218505 | 0.74 | PGR (0.31) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9215505 | 0.71 | GAA (0.38) | KMT2AHTR6 | |
| SCHEMBL9215943 | 0.71 | AVPR1B (0.35) | KMT2AAVPR1BALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |