Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 17/20 | 0.50 |
| ▸ | PYGL | P06737 | 16/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952044 | 0.86 | PYGM (0.50) | PYGMPYGL | |
| SCHEMBL6949414 | 0.79 | PYGM (0.49) | PYGMPYGL | |
| SCHEMBL6945774 | 0.76 | ALOX15 (0.44) | PYGMPYGLSMN1; SMN2GAA | |
| SCHEMBL7074756 | 0.73 | ALOX15 (0.41) | PYGMPYGLSMN1; SMN2GAATSHR | |
| SCHEMBL6944706 | 0.71 | ALOX15 (0.64) | SMN1; SMN2GAATSHR | |
| SCHEMBL6953545 | 0.71 | PYGM (0.49) | PYGMPYGL | |
| SCHEMBL6942375 | 0.70 | MAPT (0.52) | PYGMPYGLSMN1; SMN2TSHR | |
| SCHEMBL6947702 | 0.70 | PYGM (0.53) | PYGMPYGL | |
| SCHEMBL6949599 | 0.69 | ALOX15 (0.61) | SMN1; SMN2GAATSHR | |
| SCHEMBL9217791 | 0.69 | PYGM (0.67) | PYGMPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657433-A1 | Dihydropyridines with substituted esters showing cerebral activity | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |