Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | PYGM | P11217 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947856 | 0.92 | RECQL (0.45) | ALOX15GPBAR1RECQLTDP1LMNA | |
| SCHEMBL6952044 | 0.91 | PYGM (0.50) | ALOX15GPBAR1NR3C2PYGLPYGM | |
| SCHEMBL7074756 | 0.82 | ALOX15 (0.41) | ALOX15SMN1; SMN2PYGLPYGMGAA | |
| SCHEMBL6949414 | 0.82 | PYGM (0.49) | RECQLTDP1NR3C2KMT2AMEN1 | |
| SCHEMBL6945824 | 0.81 | NR3C2 (0.44) | GPBAR1RECQLTDP1LMNASMN1; SMN2 | |
| SCHEMBL6950023 | 0.81 | LMNA (0.46) | GPBAR1RECQLTDP1LMNASMN1; SMN2 | |
| SCHEMBL6942375 | 0.78 | MAPT (0.52) | ALOX15SMN1; SMN2KMT2AMEN1PYGL | |
| SCHEMBL6949655 | 0.76 | PYGL (0.44) | LMNASMN1; SMN2NR3C2PYGLPYGM | |
| SCHEMBL6945772 | 0.76 | ALOX15 (0.68) | ALOX15LMNAKMT2AMEN1KDM4E | |
| SCHEMBL9215355 | 0.76 | PYGM (0.50) | SMN1; SMN2PYGLPYGMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |