Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 16/20 | 0.38 |
| ▸ | PYGM | P11217 | 16/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945774 | 0.82 | ALOX15 (0.44) | ALOX15PYGLPYGMSMN1; SMN2GAA | |
| SCHEMBL6952044 | 0.79 | PYGM (0.50) | ALOX15PYGLPYGM | |
| SCHEMBL6947856 | 0.74 | RECQL (0.45) | ALOX15SMN1; SMN2 | |
| SCHEMBL9215355 | 0.73 | PYGM (0.50) | PYGLPYGMSMN1; SMN2GAATSHR | |
| SCHEMBL6945772 | 0.72 | ALOX15 (0.68) | ALOX15GAATSHR | |
| SCHEMBL6949414 | 0.71 | PYGM (0.49) | PYGLPYGM | |
| SCHEMBL6944706 | 0.67 | ALOX15 (0.64) | ALOX15SMN1; SMN2GAATSHR | |
| SCHEMBL6942375 | 0.67 | MAPT (0.52) | ALOX15PYGLPYGMSMN1; SMN2TSHR | |
| SCHEMBL6950055 | 0.67 | POLB (0.49) | ALOX15GAATSHR | |
| SCHEMBL6949599 | 0.65 | ALOX15 (0.61) | ALOX15SMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657431-B1 | 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity | BAYER AG (DE) | 2003-02-19 | — | — | EP | claimed |
| EP-0657431-A1 | 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity | BAYER AG (DE) | 1995-06-14 | — | — | EP | claimed |
| EP-0657431-B1 | 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity | BAYER AG (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0657431-A1 | 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |