Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 2/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195833 | 0.90 | PDE4A (0.50) | ALDH1A1KDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL9209660 | 0.85 | LMNA (0.53) | ALDH1A1KDM4ELMNAHTTNPSR1 | |
| SCHEMBL9208527 | 0.84 | ADORA3 (0.53) | ALDH1A1KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL9204351 | 0.82 | PDE1A (0.57) | ALDH1A1KDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL9208164 | 0.82 | P2RX4 (0.50) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL9215327 | 0.82 | PGR (0.59) | ALDH1A1KDM4ETDP1L3MBTL1LMNA | |
| SCHEMBL9214081 | 0.81 | PTGER4 (0.44) | ALDH1A1TSHRTDP1L3MBTL1USP2 | |
| SCHEMBL9215381 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL9206544 | 0.81 | PDE4A (0.55) | ALDH1A1KDM4ESMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL9209628 | 0.79 | ADORA3 (0.48) | ALDH1A1KDM4ESMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |