Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209660 | 0.82 | LMNA (0.53) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9208527 | 0.81 | ADORA3 (0.53) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9214076 | 0.79 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9208164 | 0.79 | P2RX4 (0.50) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9216893 | 0.79 | ALDH1A1 (0.48) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9215327 | 0.79 | PGR (0.59) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9206544 | 0.78 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9214081 | 0.78 | PTGER4 (0.44) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9215381 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL30881088 | 0.76 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |