Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209660 | 0.87 | LMNA (0.53) | KDM4EHPGDALDH1A1MAPK1 | |
| SCHEMBL9215618 | 0.83 | KDM4E (0.54) | KDM4EPOLBHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9208164 | 0.83 | P2RX4 (0.50) | KDM4EHSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL9208527 | 0.83 | ADORA3 (0.53) | KDM4EADORA2BPOLBHPGDHSD17B10 | |
| SCHEMBL9216893 | 0.81 | ALDH1A1 (0.48) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL9215327 | 0.81 | PGR (0.59) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9214081 | 0.80 | PTGER4 (0.44) | POLBHPGDALDH1A1MAPK1MEN1 | |
| SCHEMBL9206544 | 0.80 | PDE4A (0.55) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL9209628 | 0.78 | ADORA3 (0.48) | KDM4EGLAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9195923 | 0.76 | HPGD (0.57) | KDM4EHPGDHSD17B10ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |