Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212264 | 0.81 | KDM4E (0.55) | DHODHKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9217470 | 0.80 | IP6K1 (0.42) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL9217584 | 0.78 | NAAA (0.46) | HPGDPTGS2LMNANPC1RAB9A | |
| SCHEMBL9216798 | 0.78 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL9211748 | 0.78 | ADORA3 (0.49) | DHODHKDM4EALDH1A1HPGDTTR | |
| SCHEMBL9217430 | 0.76 | TBK1 (0.46) | RXRARXRBRXRGKDM4EHSD17B10 | |
| SCHEMBL9212333 | 0.73 | MAPT (0.46) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL9219756 | 0.71 | TP53 (0.51) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL9217855 | 0.71 | IP6K1 (0.48) | RXRARXRBRXRGDHODHKDM4E | |
| SCHEMBL9219862 | 0.70 | MCL1 (0.49) | KDM4EHSD17B10ALDH1A1HPGDCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |