Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201626 | 0.81 | L3MBTL1 (0.60) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9217459 | 0.81 | PTPN1 (0.50) | TBK1KDM4ERAB9AL3MBTL1HPGD | |
| SCHEMBL9217575 | 0.79 | NAAA (0.45) | TBK1NPC1RAB9A | |
| SCHEMBL8401426 | 0.78 | MCL1 (0.61) | KDM4ETTRTNKSALDH1A1HPGD | |
| SCHEMBL3610930 | 0.77 | PTPN1 (0.59) | KDM4ENPC1GAAPKML3MBTL1 | |
| SCHEMBL9217440 | 0.76 | RXRA (0.42) | TBK1KDM4ENPC1ABCC4TTR | |
| SCHEMBL9212323 | 0.74 | L3MBTL1 (0.51) | KDM4ENPC1GAAPKMRAB9A | |
| SCHEMBL5557517 | 0.74 | ALDH1A1 (0.63) | TBK1KDM4ENPC1ABCC4TTR | |
| SCHEMBL11746198 | 0.73 | ALDH1A1 (0.55) | KDM4ENPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9916152 | 0.73 | TNKS (0.47) | TBK1KDM4ENPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| CN-1067886-A | New urea derivatives, their preparation method and pharmaceutical composition thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-01-13 | — | — | CN | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |