Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217290 | 0.88 | MAPT (0.40) | RAB9AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9218108 | 0.82 | RAB9A (0.46) | RAB9AMAPTKMT2AMEN1RXFP1 | |
| SCHEMBL9220146 | 0.80 | ALDH1A1 (0.46) | RAB9AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9212356 | 0.80 | ALDH1A1 (0.46) | RAB9AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6460660 | 0.74 | MEN1 (0.53) | MAPTKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL5605989 | 0.74 | MEN1 (0.53) | MAPTKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL9214622 | 0.73 | LMNA (0.44) | RAB9AKMT2ALMNACYP2C9CYP2C19 | |
| SCHEMBL9214617 | 0.73 | LMNA (0.44) | RAB9AKMT2ALMNACYP2C9CYP2C19 | |
| SCHEMBL9601271 | 0.73 | MEN1 (0.51) | MAPTKMT2AMEN1RXFP1CYP2C9 | |
| SCHEMBL9208882 | 0.73 | MEN1 (0.51) | MAPTKMT2AMEN1RXFP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | claimed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | claimed |
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | disclosed |