Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216012 | 0.92 | TP53 (0.55) | HDAC1HDAC2NAAANPC1RAB9A | |
| SCHEMBL9219835 | 0.91 | TP53 (0.53) | HDAC1HDAC2NAAANPC1RAB9A | |
| SCHEMBL9220873 | 0.89 | EPHX1 (0.49) | HDAC1HDAC2NAAAALOX15EPHX1 | |
| SCHEMBL9222006 | 0.89 | HDAC1 (0.51) | HDAC1HDAC2NAAANPC1RAB9A | |
| SCHEMBL9216809 | 0.89 | NAAA (0.49) | HDAC1HDAC2NAAAALOX15TP53 | |
| SCHEMBL9220337 | 0.88 | L3MBTL1 (0.49) | HDAC1HDAC2NAAANPC1RAB9A | |
| SCHEMBL9218736 | 0.87 | NAAA (0.47) | HDAC1HDAC2NAAAALOX15TP53 | |
| SCHEMBL9215682 | 0.86 | HDAC1 (0.47) | HDAC1HDAC2NAAANPC1RAB9A | |
| SCHEMBL9217575 | 0.85 | NAAA (0.45) | HDAC1HDAC2NAAANPC1RAB9A | |
| SCHEMBL9210110 | 0.85 | HDAC1 (0.56) | HDAC1HDAC2NAAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| CN-1067886-A | New urea derivatives, their preparation method and pharmaceutical composition thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-01-13 | — | — | CN | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |