SCHEMBL921119

SCHEMBL921119

CC(C)Cc1ccccc1Oc1ccc(CNC(=O)c2ccc(F)nc2N)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.44
PRMT6 Q96LA8 3/20 0.44
HTT P42858 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PTGER4 P35408 2/20 0.42
PTGER2 P43116 1/20 0.42
MAPK1 P28482 4/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
PPARA Q07869 2/20 0.41
MAPK14 Q16539 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920616 0.92 PPARA (0.43) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL921959 0.91 CARM1 (0.43) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL921932 0.90 HTT (0.46) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL920821 0.90 CARM1 (0.45) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL920291 0.88 ALDH1A1 (0.46) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL921525 0.87 LIPG (0.44) CARM1PRMT6PTGER4PTGER2MAPK1
SCHEMBL921674 0.87 RIPK1 (0.44) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL919648 0.86 CARM1 (0.43) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL920777 0.86 ALDH1A1 (0.44) CARM1PRMT6HTTALDH1A1GAA
SCHEMBL922161 0.85 MAPK14 (0.56) CARM1PRMT6HTTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 CARM1 273/4885PRMT6 1994/4885HTT 2561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.