Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | RRM1 | P23921 | 2/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219603 | 0.93 | ACLY (0.33) | ACLYCHRM2CHRM1RRM1RRM2B | |
| SCHEMBL9217252 | 0.89 | HTT (0.35) | ACLYGAAGHSRRAPGEF3 | |
| SCHEMBL9220670 | 0.86 | ROCK2 (0.36) | ACLYCPT1AROCK2ROCK1 | |
| SCHEMBL9222097 | 0.83 | NPSR1 (0.34) | ACLYGAAKMT2ARAB9ATDP1 | |
| SCHEMBL9221306 | 0.80 | IDH1 (0.34) | ACLYGAAKMT2AGHSRCPT1A | |
| SCHEMBL9211589 | 0.79 | MAPT (0.37) | ACLYGAAKMT2AGHSRRAB9A | |
| SCHEMBL9217235 | 0.78 | NPSR1 (0.35) | ACLYGAAKMT2ARAB9ATDP1 | |
| SCHEMBL9217189 | 0.77 | ABCC9 (0.34) | ACLYGAAKMT2ARAB9ATDP1 | |
| SCHEMBL7467205 | 0.76 | AVPR1B (0.46) | — | |
| SCHEMBL9219472 | 0.75 | MEN1 (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |