Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222006 | 0.89 | HDAC1 (0.51) | HDAC1HDAC2ALOX15NAAAALDH1A1 | |
| SCHEMBL9219835 | 0.89 | TP53 (0.53) | EPHX1HDAC1HDAC2NAAAALDH1A1 | |
| SCHEMBL9212465 | 0.89 | HDAC1 (0.54) | EPHX1HDAC1HDAC2ALOX15NAAA | |
| SCHEMBL9215682 | 0.88 | HDAC1 (0.47) | EPHX1HDAC1HDAC2ALOX15NAAA | |
| SCHEMBL9218736 | 0.87 | NAAA (0.47) | EPHX1HDAC1HDAC2ALOX15NAAA | |
| SCHEMBL9216012 | 0.84 | TP53 (0.55) | HDAC1HDAC2NAAAALDH1A1 | |
| SCHEMBL9220885 | 0.83 | EPHX1 (0.48) | EPHX1HDAC1ALOX15EPHX2NAAA | |
| SCHEMBL9218992 | 0.83 | HDAC1 (0.50) | EPHX1HDAC1HDAC2NAAAALDH1A1 | |
| SCHEMBL9216809 | 0.81 | NAAA (0.49) | HDAC1HDAC2ALOX15NAAA | |
| SCHEMBL9220337 | 0.80 | L3MBTL1 (0.49) | HDAC1HDAC2ALOX15NAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |