SCHEMBL922124

SCHEMBL922124

NCc1ccc(Oc2ccc3c(c2)CCC3)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.58
STS P08842 1/20 0.49
MAPK14 Q16539 1/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
TP53 P04637 1/20 0.46
RXRB P28702 4/20 0.46
RXRA P19793 3/20 0.46
RXRG P48443 3/20 0.46
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TPSAB1 Q15661 1/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922347 0.98 ST14 (0.60) ST14STSMAPK14NPC1RAB9A
SCHEMBL923237 0.89 ALDH1A1 (0.47) ST14STSMAPK14NPC1RAB9A
SCHEMBL921772 0.89 ST14 (0.49) ST14STSMAPK14NPC1RAB9A
SCHEMBL27415227 0.83 STS (0.53) STSNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31312960 0.83 STS (0.59) STSMAPK14NPC1RAB9ASMN1; SMN2
SCHEMBL9502785 0.83 MAPK14 (0.46) STSMAPK14NPC1RAB9ASMN1; SMN2
SCHEMBL13922867 0.81 NPC1 (0.48) STSMAPK14NPC1RAB9ASMN1; SMN2
SCHEMBL9502151 0.81 ALOX15 (0.46) STSMAPK14NPC1RAB9ASMN1; SMN2
SCHEMBL12238988 0.81 ROCK2 (0.58) ST14STSMAPK14NPC1RAB9A
SCHEMBL5408563 0.80 ALDH1A1 (0.54) STSNPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885STS 175/4885MAPK14 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.