SCHEMBL923237

SCHEMBL923237

NCc1cccc(Oc2ccc3c(c2)CCC3)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
GAA P10253 2/20 0.47
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 6/20 0.46
RAB9A P51151 6/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
POLB P06746 1/20 0.46
GFER P55789 1/20 0.46
PAX8 Q06710 1/20 0.46
KLF5 Q13887 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ST14 Q9Y5Y6 1/20 0.44
MAPK14 Q16539 1/20 0.43
CETP P11597 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
STS P08842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921772 0.97 ST14 (0.49) ALDH1A1MAPTGAAKDM4ENPC1
SCHEMBL922124 0.89 ST14 (0.58) ALDH1A1MAPTGAANPC1RAB9A
SCHEMBL922347 0.87 ST14 (0.60) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL4949955 0.81 ST14 (0.58) ALDH1A1MAPTGAASMN1; SMN2GFER
SCHEMBL27907657 0.81 LOXL2 (0.47) ALDH1A1KDM4ESMN1; SMN2HPGDST14
SCHEMBL27415227 0.79 STS (0.53) ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL21758061 0.78 HRH3 (0.62) NPC1RAB9ASMN1; SMN2POLBGFER
SCHEMBL12238988 0.77 ROCK2 (0.58) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1301847 0.76 LOXL2 (0.58) ALDH1A1KDM4ESMN1; SMN2HPGDST14
SCHEMBL11961604 0.76 ALDH1A1 (0.54) ALDH1A1MAPTGAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ALDH1A1 2743/4885MAPT 695/4885GAA 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.