SCHEMBL9224928

SCHEMBL9224928

COc1ccc(Nc2ccc(N=O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.68
▸ RAB9A P51151 5/20 0.68
▸ GAA P10253 4/20 0.68
▸ TDP1 Q9NUW8 3/20 0.68
▸ MAPK1 P28482 3/20 0.68
▸ NPC1 O15118 3/20 0.68
▸ L3MBTL1 Q9Y468 3/20 0.68
▸ KDM4E B2RXH2 3/20 0.68
▸ THRB P10828 1/20 0.68
▸ RECQL P46063 1/20 0.68
▸ NPSR1 Q6W5P4 1/20 0.68
▸ ALDH1A1 P00352 6/20 0.59
▸ HTT P42858 4/20 0.59
▸ HSD17B10 Q99714 3/20 0.59
▸ TSHR P16473 2/20 0.59
▸ CYP3A4 P08684 1/20 0.59
▸ NR4A1 P22736 1/20 0.57
▸ ALOX12 P18054 1/20 0.47
▸ SMN1; SMN2 Q16637 5/20 0.47
▸ APP P05067 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156005 0.87 CA1 (0.58) TDP1MAPK1ALDH1A1HSD17B10TSHR
SCHEMBL39057 0.82 MAPT (1.00) MAPTRAB9AGAATDP1MAPK1
SCHEMBL1459772 0.82 MAPT (1.00) MAPTRAB9AGAATDP1MAPK1
SCHEMBL10311786 0.80 NPC1 (0.68) MAPTRAB9AGAATDP1MAPK1
SCHEMBL14104855 0.80 MAPT (0.68) MAPTRAB9AGAATDP1MAPK1
SCHEMBL9218582 0.79 KMT2A (0.54) MAPTTDP1MAPK1L3MBTL1KDM4E
SCHEMBL22783761 0.78 S100B (0.68) MAPTRAB9AGAATDP1MAPK1
SCHEMBL10311785 0.78 RAB9A (0.78) MAPTRAB9AGAANPC1KDM4E
SCHEMBL8044644 0.77 RAB9A (0.63) MAPTRAB9AGAATDP1MAPK1
SCHEMBL28233594 0.77 MAPT (0.63) MAPTRAB9AGAATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403797-B1 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN KK (JP) 1995-11-22 — — EP claimed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 — — EP claimed
US-20110046378-A1 Novel Imaging Agents for Detecting Neurological Dysfunction SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2011-02-24 — — US disclosed
EP-0403797-B1 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN KK (JP) 1995-11-22 — — EP disclosed
US-5318882-A Nitrosodiphenylamine compounds render dyes lightfast TAIYO YUDEN CO., LTD. (JP) 1994-06-07 — — US disclosed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 — — EP disclosed
US-4304939-A Preparation of N-phenyl-N-alkylphenylenediamines UOP INC. (US) 1981-12-08 — — US disclosed
US-4163015-A ANTIBACTERIAL AGENTS STERLING DRUG INC. (US) 1979-07-31 — — US disclosed
US-4138405-A BACTERICIDES STERLING DRUG INC. (US) 1979-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046378-A1 Novel Imaging Agents for Detecting Neurological Dysfunction FABP7, SLC18A3, TSPO MAPT 35/4885RAB9A 1606/4885GAA 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback