Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.60 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.60 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.60 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228703 | 0.82 | HTR6 (0.54) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL10974178 | 0.82 | HSD11B1 (0.61) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL13884294 | 0.82 | ALDH1A1 (0.55) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| Hydrochloric Acid SCHEMBL9231987 | 0.80 | HTR6 (0.52) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL9232563 | 0.79 | CA1 (0.50) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL9233513 | 0.79 | MTNR1B (0.62) | ABCC9ABCC8KCNJ11KCNJ8PGR | |
| SCHEMBL27760546 | 0.79 | ABCC9 (0.78) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 | |
| SCHEMBL9234066 | 0.79 | ALDH1A1 (0.46) | HSD11B1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL13884299 | 0.79 | SMN1; SMN2 (0.58) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL2035375 | 0.78 | ALDH1A1 (0.67) | ABCC9ABCC8KCNJ11KCNJ8HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |