Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8867217 | 0.89 | SUV39H2 (0.43) | SUV39H2CHRM4TPSAB1S1PR1HDAC4 | |
| Trifluoroacetic Acid SCHEMBL9230148 | 0.88 | HPGDS (0.41) | SUV39H2LOXL2FFAR1HDAC4 | |
| SCHEMBL9236237 | 0.82 | ALDH1A1 (0.41) | SUV39H2 | |
| Trifluoroacetic Acid SCHEMBL8866439 | 0.81 | LOXL2 (0.48) | SUV39H2CHRM4LOXL2S1PR1FFAR1 | |
| Trifluoroacetic Acid SCHEMBL9233235 | 0.80 | HPGDS (0.42) | SUV39H2 | |
| SCHEMBL9235366 | 0.79 | SUV39H2 (0.44) | SUV39H2CHRM4TPSAB1 | |
| SCHEMBL9235823 | 0.79 | SUV39H2 (0.44) | SUV39H2CHRM4TLR9TLR7 | |
| Trifluoroacetic Acid SCHEMBL9229650 | 0.79 | HPGDS (0.42) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL8866276 | 0.77 | HPGDS (0.43) | S1PR1FFAR1HDAC4 | |
| Trifluoroacetic Acid SCHEMBL9232906 | 0.76 | HTR2A (0.42) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |