Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051337 | 0.85 | SMN1; SMN2 (0.70) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL20278348 | 0.84 | MAPT (0.57) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL1687863 | 0.84 | ALDH1A1 (0.64) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL5630152 | 0.84 | KMT2A (0.60) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL14230567 | 0.81 | MAPT (0.54) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL13844915 | 0.81 | PRSS1 (0.48) | L3MBTL1RAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL28234292 | 0.81 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| Ethyne SCHEMBL8050785 | 0.80 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL2643703 | 0.80 | LOXL2 (0.57) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A | |
| SCHEMBL11037686 | 0.80 | MAPT (0.53) | MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603436-A | Polymer, modified polyurethane elastomer and preparation method thereof | 北京大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-108440535-A | Metal fullerene nitroxide free-radical derivative and its preparation method and application | 中国科学院化学研究所 | 2018-08-24 | — | — | CN | disclosed |
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| EP-3287453-A1 | IMIDAZOLE COMPOUND | Medshine Discovery Inc. (CN) | 2018-02-28 | — | — | EP | disclosed |
| US-20150266860-A1 | CRYSTALLINE FORM OF A DRUG | ABBVIE INC. (US) | 2015-09-24 | — | — | US | disclosed |
| CN-104903320-A | Nitrogen-containing heterocylic compound or salt thereof | FUJIFILM CORP | 2015-09-09 | — | — | CN | disclosed |
| US-8278387-B2 | Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate | FUJIFILM CORPORATION (JP) | 2012-10-02 | — | — | US | disclosed |
| US-20120165309-A1 | HETERO RING DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20090246469-A1 | RESIN COMPOSITION FOR LASER ENGRAVING, IMAGE FORMING MATERIAL, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF MANUFACTURING RELIEF PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20070078173-A1 | Alpha- and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 2007-04-05 | — | — | US | disclosed |
| CN-1265651-A | Novel tricyclic compound having saturated ring and pharmaceutical composition thereof | ASAHI CHEMICAL IND (JP) | 2000-09-06 | — | — | CN | disclosed |
| EP-0664316-A1 | Polycarbonate composition having improved resistance to gamma-ray radiation | TEIJIN LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MAPT, SLC10A2, SLC5A11 | MAPT 1/4885SMN1; SMN2 775/4885L3MBTL1 4775/4885 |
| US-20120165309-A1 | HETERO RING DERIVATIVE | IL2, PIK3R2, IL2RA | MAPT 3968/4885SMN1; SMN2 4237/4885L3MBTL1 1818/4885 |
| US-20070078173-A1 | Alpha- and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | DNPEP, ASPH, PREP | MAPT 2279/4885SMN1; SMN2 2396/4885L3MBTL1 1142/4885 |
| US-20150266860-A1 | CRYSTALLINE FORM OF A DRUG | REN, AGTR1, TTR | MAPT 888/4885SMN1; SMN2 1465/4885L3MBTL1 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.