SCHEMBL9240920

SCHEMBL9240920

O=C(Cc1ccccc1)c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 3/20 0.58
SRD5A2 P31213 2/20 0.56
MAPT P10636 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KLKB1 P03952 1/20 0.51
CTSB P07858 1/20 0.51
MMP9 P14780 1/20 0.51
DNMT1 P26358 1/20 0.51
DNMT3B Q9UBC3 1/20 0.51
DNMT3L Q9UJW3 1/20 0.51
DNMT3A Q9Y6K1 1/20 0.51
ACMSD Q8TDX5 5/20 0.51
RAB9A P51151 2/20 0.51
PLAU P00749 1/20 0.51
KDM4E B2RXH2 1/20 0.51
NPC1 O15118 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MCL1 Q07820 2/20 0.50
DHFR P00374 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10351730 0.84 MAPT (0.58) SRD5A2MAPTL3MBTL1RAB9APLAU
SCHEMBL11534522 0.80 LDHA (0.52) HNF4AKLKB1CTSBMMP9DNMT1
SCHEMBL4296416 0.80 LMNA (0.56) SRD5A2MAPTL3MBTL1RAB9APLAU
SCHEMBL10705887 0.79 AKR1B1 (0.55) SRD5A2MAPTL3MBTL1RAB9APLAU
SCHEMBL7129800 0.78 MAPT (0.80) SRD5A2MAPTL3MBTL1RAB9APLAU
SCHEMBL11447833 0.77 CA1 (0.52) HNF4AMAPTL3MBTL1KLKB1CTSB
SCHEMBL3947199 0.77 PTPN1 (0.52) HNF4AMAPTL3MBTL1KLKB1CTSB
SCHEMBL1360224 0.77 KDM4E (0.53) HNF4AMAPTL3MBTL1KLKB1CTSB
SCHEMBL1576999 0.77 CSNK2A1 (0.53) HNF4AMAPTL3MBTL1KLKB1CTSB
SCHEMBL1405708 0.77 CA1 (0.53) HNF4AMAPTL3MBTL1KLKB1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7267965-A None JP disclosed
JP-H07267965-A ZINC SALT HYDRATE OF SALICYLIC ACID DERIVATIVE, ITS PRODUCTION AND HEAT-SENSITIVE RECORDING MATERIAL USING THE SAME MITSUI TOATSU CHEM INC 1995-10-17 JP disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed