Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243441 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDALOX15HSD17B10NPSR1 | |
| SCHEMBL9133694 | 0.75 | ALOX15 (0.43) | ALDH1A1HPGDALOX15HSD17B10TP53 | |
| SCHEMBL8919988 | 0.74 | HPGD (0.42) | ALDH1A1HPGDALOX15HSD17B10NPSR1 | |
| SCHEMBL8921644 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL9133737 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDALOX15HSD17B10NPSR1 | |
| SCHEMBL9131341 | 0.72 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10NPSR1 | |
| SCHEMBL9132104 | 0.68 | ALDH1A1 (0.65) | ALDH1A1HPGDALOX15HSD17B10TP53 | |
| SCHEMBL11199209 | 0.66 | LGMN (0.55) | ALDH1A1HSD17B10NPSR1TP53MAPT | |
| SCHEMBL8921445 | 0.66 | HPGD (0.62) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL8921982 | 0.66 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414082-A | Anticonvulsants | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1995-05-09 | — | — | US | disclosed |