Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251669 | 0.87 | TMPRSS15 (0.39) | TMPRSS15ITGB3ITGA2BCYP1A2CYP3A4 | |
| SCHEMBL9255137 | 0.82 | TMPRSS15 (0.41) | TMPRSS15ITGB3ITGA2BCYP1A2CYP3A4 | |
| SCHEMBL9249034 | 0.80 | TMPRSS15 (0.40) | TMPRSS15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9251663 | 0.78 | TMPRSS15 (0.39) | TMPRSS15ITGB3ITGA2BCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8949354 | 0.77 | ITGB3 (0.41) | TMPRSS15ITGB3ITGA2BF2F10 | |
| SCHEMBL9256431 | 0.77 | ITGB3 (0.38) | TMPRSS15ITGB3ITGA2BCYP1A2CYP2C9 | |
| SCHEMBL9255399 | 0.73 | SCN9A (0.42) | TMPRSS15ITGB3ITGA2BF2F10 | |
| SCHEMBL9252818 | 0.72 | ADORA3 (0.41) | TMPRSS15ITGB3ITGA2BCHEK2ADORA3 | |
| SCHEMBL9254810 | 0.70 | VCP (0.41) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8887529 | 0.70 | F2 (0.45) | TMPRSS15F2F10FASNNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |