Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256431 | 0.91 | ITGB3 (0.38) | TMPRSS15CYP1A2CYP2C9MELKDYRK1A | |
| SCHEMBL9249043 | 0.87 | TMPRSS15 (0.40) | TMPRSS15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9249034 | 0.83 | TMPRSS15 (0.40) | TMPRSS15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9251663 | 0.81 | TMPRSS15 (0.39) | TMPRSS15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9255137 | 0.80 | TMPRSS15 (0.41) | TMPRSS15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9254810 | 0.74 | VCP (0.41) | ITGB3ITGA2B | |
| SCHEMBL9251738 | 0.71 | PADI4 (0.43) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9255399 | 0.71 | SCN9A (0.42) | TMPRSS15F2F10CHEK2ITGB3 | |
| SCHEMBL9252818 | 0.70 | ADORA3 (0.41) | TMPRSS15CHEK2ITGB3ITGA2B | |
| SCHEMBL9251783 | 0.68 | TMPRSS15 (0.45) | TMPRSS15CYP1A2CYP2C9F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |