SCHEMBL9249142

SCHEMBL9249142

O=C(NOc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 8/20 0.50
CES1 P23141 8/20 0.50
TSHR P16473 2/20 0.42
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PARP1 P09874 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
PARP10 Q53GL7 1/20 0.41
METAP2 P50579 3/20 0.41
METAP1 P53582 2/20 0.41
PGR P06401 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6508655 0.81 METAP2 (0.44) KMT2APARP10METAP2METAP1MEN1
SCHEMBL126697 0.79 ALDH1A1 (0.59) MAPTPOLBHSD17B10KMT2AALDH1A1
SCHEMBL28238162 0.79 CES2 (0.54) CES2CES1TSHRMAPTPOLB
SCHEMBL29129938 0.79 MEN1 (0.44) TSHRMAPTPOLBCYP3A4TDP1
SCHEMBL20711451 0.78 ALDH1A1 (0.42) MAPTKMT2AALDH1A1PARP10METAP2
SCHEMBL26805580 0.78 METAP2 (0.42) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL3590919 0.76 METAP2 (0.46) TSHRKMT2APARP10METAP2METAP1
SCHEMBL7504360 0.74 CES2 (0.59) CES2CES1TSHRMAPTPOLB
SCHEMBL10728474 0.74 METAP2 (0.45) TSHRKMT2APARP10METAP2METAP1
SCHEMBL3646258 0.74 MEN1 (0.52) TSHRMAPTPOLBCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7188140-A None JP disclosed
JP-H07188140-A PRODUCTION OF PHENOXYBENZOYLFORMIC ACID AMIDE MITSUI TOATSU CHEM INC 1995-07-25 JP disclosed