SCHEMBL6508655

SCHEMBL6508655

O=C(O)C(=O)NOc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 8/20 0.44
METAP1 P53582 7/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPN1 P18031 2/20 0.41
PARP10 Q53GL7 1/20 0.41
PTPN11 Q06124 1/20 0.41
CDK5 Q00535 2/20 0.41
CDK5R1 Q15078 2/20 0.41
CCNA2 P20248 1/20 0.41
CDK2 P24941 1/20 0.41
CCNA1 P78396 1/20 0.41
ALOX15 P16050 1/20 0.40
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
GPR35 Q9HC97 1/20 0.39
CTNNB1 P35222 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29129938 0.84 MEN1 (0.44) METAP2METAP1MEN1KMT2APARP10
SCHEMBL20711451 0.83 ALDH1A1 (0.42) METAP2METAP1MEN1KMT2APARP10
SCHEMBL26805580 0.83 METAP2 (0.42) METAP2METAP1MEN1KMT2A
SCHEMBL3590919 0.81 METAP2 (0.46) METAP2METAP1MEN1KMT2APARP10
SCHEMBL9249142 0.81 CES2 (0.50) METAP2METAP1MEN1KMT2APARP10
SCHEMBL3646258 0.79 MEN1 (0.52) METAP2METAP1MEN1KMT2APARP10
SCHEMBL10728474 0.79 METAP2 (0.45) METAP2METAP1MEN1KMT2APARP10
SCHEMBL873554 0.77 PARP10 (0.45) METAP2METAP1MEN1KMT2APARP10
SCHEMBL31050921 0.77 METAP2 (0.44) METAP2METAP1MEN1KMT2APARP10
SCHEMBL873555 0.77 MTNR1A (0.48) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 METAP2 3702/4885METAP1 2800/4885MEN1 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.