Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 6/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254058 | 0.85 | PKM (0.40) | MAPK1PKMPKLRALDH1A1PHGDH | |
| SCHEMBL10473053 | 0.74 | IDO1 (0.44) | LMNAMAPTTDP1PGRCYP3A4 | |
| SCHEMBL9253004 | 0.68 | LMNA (0.58) | LMNAMAPTCYP2D6HTTALDH1A1 | |
| SCHEMBL9256000 | 0.68 | ALDH1A1 (0.63) | PKMALDH1A1PHGDHMGLLCA1 | |
| Hydrochloric Acid SCHEMBL9252823 | 0.68 | LMNA (0.57) | LMNAMAPTCYP2D6HTTALDH1A1 | |
| SCHEMBL9253292 | 0.68 | PHGDH (0.35) | TDP1CYP2C9CYP2C19ALDH1A1PHGDH | |
| Hydrochloric Acid SCHEMBL9257450 | 0.67 | ALDH1A1 (0.62) | PKMALDH1A1PHGDHMGLLCA1 | |
| SCHEMBL9253999 | 0.67 | SIGMAR1 (0.64) | LMNAMAPTHTTALDH1A1PHGDH | |
| SCHEMBL9253056 | 0.66 | CA1 (0.32) | LMNAMAPTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9255506 | 0.66 | KMT2A (0.58) | LMNAMAPTTDP1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |