Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254231 | 0.90 | AGTR1 (0.44) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9250685 | 0.90 | SMO (0.34) | MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL8806788 | 0.89 | AGTR1 (0.42) | DHFRGAARAB9AARALDH1A1 | |
| SCHEMBL9249723 | 0.87 | ALDH1A1 (0.45) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL9250323 | 0.85 | DHFR (0.44) | DHFRARMAPTSMN1; SMN2CYP4A11 | |
| SCHEMBL8807918 | 0.78 | AGTR1 (0.40) | ALDH1A1 | |
| SCHEMBL9254655 | 0.78 | AGTR1 (0.42) | ALDH1A1 | |
| SCHEMBL1228189 | 0.78 | AGTR1 (0.53) | ALDH1A1 | |
| SCHEMBL9257344 | 0.78 | KDM4E (0.42) | RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL9256658 | 0.76 | PPARG (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |