Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807918 | 0.90 | AGTR1 (0.40) | SMOPTGS1AGTR1AGTR2 | |
| SCHEMBL9250317 | 0.90 | DHFR (0.40) | MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL9254231 | 0.88 | AGTR1 (0.44) | POLBL3MBTL1SMN1; SMN2AGTR1AGTR2 | |
| Acetic Acid SCHEMBL9250689 | 0.86 | AGTR1 (0.34) | SMOPTGS1AGTR1AGTR2 | |
| SCHEMBL9249723 | 0.84 | ALDH1A1 (0.45) | POLBL3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8806788 | 0.79 | AGTR1 (0.42) | MAPTSMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL9249385 | 0.78 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9254655 | 0.76 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL1228189 | 0.76 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9257344 | 0.76 | KDM4E (0.42) | L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |