Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238216 | 0.89 | DUT (0.38) | DUTTSHRESR1ESR2TP53 | |
| SCHEMBL703379 | 0.87 | ESR1 (0.37) | DUTTSHRESR1ESR2TP53 | |
| SCHEMBL3482014 | 0.80 | HPGD (0.39) | DUTTSHRNPC1ALDH1A1HPGD | |
| SCHEMBL8639537 | 0.79 | L3MBTL1 (0.33) | DUTTSHRESR1ESR2TP53 | |
| SCHEMBL3482491 | 0.78 | TP53 (0.48) | TP53KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL15863932 | 0.78 | DUT (0.33) | DUTL3MBTL1LTA4H | |
| SCHEMBL7746293 | 0.78 | TSHR (0.31) | TSHRLTA4H | |
| SCHEMBL854785 | 0.78 | TSHR (0.36) | TSHRESR1ESR2TP53KDM4E | |
| SCHEMBL3481888 | 0.77 | MAPT (0.34) | DUTTSHRTP53KDM4ENPC1 | |
| SCHEMBL5951030 | 0.76 | TSHR (0.35) | TSHRESR1ESR2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320145-B1 | Process for the production of olefin polymerisation catalysts | SHELL OIL CO (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0320145-A2 | Process for the production of olefin polymerisation catalysts | SHELL OIL COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |