Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255947 | 0.85 | NPC1 (0.47) | NPC1RAB9ALMNAMAPK1L3MBTL1 | |
| SCHEMBL27776094 | 0.85 | NPC1 (0.48) | NPC1RAB9APTPN1HTR7KDM4E | |
| SCHEMBL10878397 | 0.83 | POLB (0.57) | NPC1RAB9APTPN1KDM4ELMNA | |
| SCHEMBL9258798 | 0.83 | CES2 (0.43) | RAB9ALMNAMAPK1KMT2AMEN1 | |
| SCHEMBL9254905 | 0.82 | NPC1 (0.46) | NPC1RAB9AKDM4ELMNAL3MBTL1 | |
| SCHEMBL9254186 | 0.79 | GSK3B (0.50) | KDM4EMAPK1PKMKMT2AMEN1 | |
| SCHEMBL1121843 | 0.77 | NPC1 (0.55) | NPC1RAB9APTPN1HTR7KDM4E | |
| SCHEMBL19219873 | 0.77 | NPC1 (0.55) | NPC1RAB9APTPN1HTR7KDM4E | |
| SCHEMBL9254114 | 0.76 | THRB (0.40) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL11548835 | 0.75 | TRPA1 (0.45) | NPC1RAB9APTPN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401768-A | Prostaglandin derivative, antiulcer, hypotensive, anticoagulant | TORAY INDUSTRIES, INC. (JP) | 1995-03-28 | — | — | US | disclosed |