Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KIF11 | P52732 | 5/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398877 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KIF11JAK2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2846560 | 0.96 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KIF11JAK2L3MBTL1 | |
| SCHEMBL12636456 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KIF11JAK2L3MBTL1 | |
| SCHEMBL17840160 | 0.83 | KIF11 (0.68) | ALDH1A1HSD17B10KIF11JAK2TSHR | |
| SCHEMBL8025255 | 0.81 | KIF11 (0.65) | ALDH1A1HSD17B10KIF11JAK2TSHR | |
| SCHEMBL28607330 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KIF11L3MBTL1TSHR | |
| SCHEMBL6480845 | 0.80 | ALDH1A1 (0.83) | ALDH1A1HSD17B10L3MBTL1TSHRKDM4E | |
| SCHEMBL5647970 | 0.79 | KIF11 (0.47) | ALDH1A1KIF11JAK2TSHRPTGS1 | |
| SCHEMBL28930463 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL4574243 | 0.79 | KIF11 (0.56) | ALDH1A1HSD17B10KIF11JAK2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5471002-A | Process for preparing trifluoromethylanilines | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 1995-11-28 | — | — | US | disclosed |