Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860104 | 0.75 | SMN1; SMN2 (0.41) | MAPTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL9440693 | 0.72 | NISCH (0.52) | CYP1A2CYP2D6CYP2C19THRBHTR1A | |
| SCHEMBL23954464 | 0.70 | IDO1 (0.59) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7859944 | 0.69 | HTR1A (0.41) | MAPTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7861309 | 0.69 | HTR6 (0.40) | MAPTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7860121 | 0.69 | NISCH (0.34) | MAPTL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL7860112 | 0.68 | NISCH (0.31) | MAPTL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL7859925 | 0.68 | HTR1A (0.46) | MAPTL3MBTL1MEN1KMT2ATP53 | |
| SCHEMBL7862260 | 0.67 | CYP19A1 (0.34) | NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL7860101 | 0.67 | ADRA2A (0.46) | SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407954-A | Serotonin antagonism; treats depression, anxiety, hypertension and migraine headaches | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-18 | — | — | US | disclosed |