Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9157724 | 0.99 | MAPT (0.50) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL8797906 | 0.89 | NPC1 (0.46) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL9122304 | 0.89 | ACHE (0.51) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL9156660 | 0.88 | NPC1 (0.45) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL8798778 | 0.80 | MTNR1A (0.60) | KDM4EALDH1A1HPGDRAB9ACYP1A2 | |
| SCHEMBL9244949 | 0.80 | KDM4E (0.50) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL19141722 | 0.80 | ACHE (0.47) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL25459991 | 0.76 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL25459999 | 0.75 | CA2 (0.57) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11798029 | 0.74 | MAPT (0.51) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386034-A | Treatment of sleeping, psychological and nervous system disorders; anxiolytic agents, ovulation regulators | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | disclosed |
| US-5322849-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-06-21 | — | — | US | disclosed |
| US-5300507-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-04-05 | — | — | US | disclosed |
| US-5240919-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |