Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.37 |
| ▸ | F10 | P00742 | 7/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257803 | 0.92 | MAPT (0.35) | F2F10PRSS1MAPT | |
| SCHEMBL8863938 | 0.90 | TMPRSS15 (0.36) | F2F10PDK1ITGB3ITGA2B | |
| SCHEMBL9254692 | 0.89 | F10 (0.34) | F2F10PDK1PRSS1USP2 | |
| SCHEMBL9257250 | 0.88 | PDK1 (0.31) | PDK1RAB9ANPC1 | |
| SCHEMBL9255067 | 0.87 | PDK1 (0.33) | PDK1EP300RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9568440 | 0.86 | ITGB3 (0.39) | F2F10PDK1ITGB3ITGA2B | |
| SCHEMBL9251525 | 0.85 | MIF (0.37) | PDK1ITGB3ITGA2BNPC1 | |
| SCHEMBL9255073 | 0.83 | PIK3CA (0.32) | F2F10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9253978 | 0.82 | ITGB3 (0.37) | F2F10PDK1ITGB3ITGA2B | |
| SCHEMBL9250531 | 0.82 | F2 (0.35) | F2PDK1ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |