Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257176 | 0.86 | CSNK2A2 (0.43) | F2F10PRSS1CSNK2A2CSNK2A1 | |
| SCHEMBL9250720 | 0.83 | SMN1; SMN2 (0.39) | CSNK2A2CSNK2A1KDM4EALDH1A1HPGD | |
| SCHEMBL9254531 | 0.81 | TMPRSS15 (0.43) | F2F10PRSS1CSNK2A2CSNK2A1 | |
| SCHEMBL9247290 | 0.77 | TMPRSS15 (0.35) | F2F10CSNK2A2CSNK2A1NR1H4 | |
| SCHEMBL9257438 | 0.76 | ITGB3 (0.46) | F2PRSS1CSNK2A2CSNK2A1ITGB3 | |
| SCHEMBL9255799 | 0.75 | F10 (0.41) | F2F10PRSS1RAB9AITGB3 | |
| SCHEMBL9255491 | 0.73 | CSNK2A2 (0.46) | CSNK2A2CSNK2A1NR1H4KDM4ERAB9A | |
| SCHEMBL9255636 | 0.73 | TMPRSS15 (0.39) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL9253457 | 0.72 | PRSS1 (0.41) | F2F10PRSS1RAB9AITGB3 | |
| SCHEMBL9254692 | 0.71 | F10 (0.34) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |