Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 11/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 11/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257116 | 0.90 | CSNK2A2 (0.42) | CSNK2A2CSNK2A1KDM4ERAB9AMAPT | |
| SCHEMBL9255491 | 0.82 | CSNK2A2 (0.46) | CSNK2A2CSNK2A1KDM4ERAB9AMAPT | |
| SCHEMBL9254531 | 0.79 | TMPRSS15 (0.43) | CSNK2A2CSNK2A1MAPTHDAC6HPGD | |
| SCHEMBL9260202 | 0.79 | SMN1; SMN2 (0.39) | CSNK2A2CSNK2A1KDM4ERAB9AMAPT | |
| SCHEMBL9257842 | 0.73 | HRH3 (0.34) | RAB9AMAPTNPC1HPGDTSHR | |
| SCHEMBL9254764 | 0.73 | EPHX1 (0.38) | RAB9AHDAC6KMT2AGLSSMN1; SMN2 | |
| SCHEMBL9250720 | 0.73 | SMN1; SMN2 (0.39) | CSNK2A2CSNK2A1KDM4EHDAC6HPGD | |
| SCHEMBL9256954 | 0.71 | CYP11B1 (0.47) | KDM4ERAB9AMAPTNPC1KMT2A | |
| SCHEMBL9247290 | 0.71 | TMPRSS15 (0.35) | CSNK2A2CSNK2A1RAB9ANR1H4HDAC6 | |
| SCHEMBL9250749 | 0.71 | ALOX5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |