Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | C5 | P01031 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256519 | 0.85 | ALDH1A1 (0.52) | KMT2AMEN1GAAPLK1MAPT | |
| SCHEMBL9255477 | 0.84 | PKM (0.44) | PTPN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL8768859 | 0.71 | NPC1 (0.42) | PTPN1KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL8767702 | 0.69 | L3MBTL1 (0.45) | POLBGAACYP1A2LMNAMAPT | |
| SCHEMBL8767887 | 0.68 | PPARA (0.43) | NPSR1KMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL23924441 | 0.68 | PTPN1 (0.75) | PTPN1NPSR1KMT2AMEN1POLB | |
| SCHEMBL29406212 | 0.68 | PTPN1 (0.75) | PTPN1NPSR1KMT2AMEN1POLB | |
| SCHEMBL13936650 | 0.67 | KMT2A (0.49) | NPSR1KMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL20897099 | 0.65 | GAA (0.50) | KMT2ASMN1; SMN2MEN1POLBGAA | |
| SCHEMBL15093649 | 0.65 | TACR3 (0.55) | NPSR1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422373-A | An alkoxybenzyl-alkylene-arylurea anticholesterol, antilipemic agents and enzyme inhibitors | BURROUGHS WELLCOME CO. (US) | 1995-06-06 | — | — | US | disclosed |