Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256519 | 0.84 | ALDH1A1 (0.52) | KMT2AHSD17B10MAPT | |
| SCHEMBL9254553 | 0.84 | PTPN1 (0.47) | POLBKMT2AMAPTPTPN1SMN1; SMN2 | |
| SCHEMBL9577665 | 0.75 | SOAT1 (0.61) | PPARGPPARA | |
| SCHEMBL3285024 | 0.67 | RARB (0.56) | PPARGPPARAKMT2AMAPTHTT | |
| SCHEMBL27265696 | 0.65 | EPHX2 (0.69) | PKMKMT2AHTTRAB9A | |
| SCHEMBL4129794 | 0.65 | EPHX2 (0.69) | PKMKMT2AHTTRAB9A | |
| SCHEMBL9848447 | 0.63 | RAB9A (0.54) | PKMHTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4133118 | 0.62 | POLB (0.58) | PKMPOLBHSD17B10HTTRAB9A | |
| SCHEMBL4787195 | 0.62 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL17049552 | 0.62 | PKM (0.70) | PKMPOLBKMT2AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422373-A | An alkoxybenzyl-alkylene-arylurea anticholesterol, antilipemic agents and enzyme inhibitors | BURROUGHS WELLCOME CO. (US) | 1995-06-06 | — | — | US | disclosed |