Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.36 |
| ▸ | CPB1 | P15086 | 5/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568520 | 0.90 | PDK1 (0.36) | CPB2CPB1PDK1MAP4K4F10 | |
| Hydrochloric Acid SCHEMBL9256051 | 0.89 | PDK1 (0.36) | CPB2CPB1PDK1MAP4K4F10 | |
| SCHEMBL9258718 | 0.89 | CPB1 (0.39) | CPB2CPB1PDK1F10F9 | |
| SCHEMBL8863320 | 0.88 | F10 (0.36) | CPB2CPB1PDK1F10F2 | |
| Hydrochloric Acid SCHEMBL9253007 | 0.88 | F10 (0.36) | CPB2CPB1PDK1F10F2 | |
| SCHEMBL9248830 | 0.87 | CPB2 (0.42) | CPB2CPB1PDK1F10F9 | |
| SCHEMBL9251486 | 0.86 | ITGB3 (0.36) | CPB2CPB1PDK1MAP4K4F10 | |
| SCHEMBL9254452 | 0.84 | CPB1 (0.37) | CPB2CPB1PDK1F10F9 | |
| SCHEMBL9568440 | 0.83 | ITGB3 (0.39) | PDK1MAP4K4F10F2PRSS1 | |
| SCHEMBL9254389 | 0.83 | F10 (0.40) | CPB2CPB1F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |