Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 10/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258114 | 0.80 | SLC6A4 (0.66) | MPOSLC6A4 | |
| SCHEMBL5584045 | 0.79 | MPO (0.73) | MPOSLC6A4 | |
| SCHEMBL9256337 | 0.78 | HTR7 (0.70) | MPOSLC6A4HTR1D | |
| SCHEMBL7866630 | 0.78 | MPO (0.64) | MPOMAPTSNCASIRT1HTR1D | |
| SCHEMBL9264998 | 0.77 | HTR7 (0.72) | MPOSLC6A4HTR1D | |
| SCHEMBL9263244 | 0.76 | GPR84 (0.64) | MPOHTR1DNOTUMPOLBMTNR1A | |
| SCHEMBL5583919 | 0.75 | MPO (0.72) | MPOSLC6A4 | |
| Hydrochloric Acid SCHEMBL11354169 | 0.74 | HTR7 (0.67) | MAPTSNCAHTR1DPOLBSMN1; SMN2 | |
| Pyrrole SCHEMBL9258023 | 0.73 | HTR7 (0.62) | MPOHTR1D | |
| SCHEMBL11355422 | 0.73 | MAPT (0.65) | MAPTSNCASIRT1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |