Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 4/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261099 | 0.84 | LMNA (0.53) | LMNARXRARXRBLTB4RPPARD | |
| SCHEMBL9254650 | 0.83 | HTR1A (0.40) | SLC6A9LTB4RPRMT6HSD17B1HSD17B2 | |
| SCHEMBL9259713 | 0.80 | LMNA (0.50) | LMNAPRMT6HSD17B1HSD17B2 | |
| SCHEMBL9260900 | 0.78 | LTB4R (0.45) | LMNACTSASLC6A9RXRARXRB | |
| SCHEMBL9256522 | 0.77 | PRMT6 (0.48) | LMNASLC6A9RXRARXRBPRMT6 | |
| SCHEMBL9255957 | 0.75 | HTR1A (0.40) | CTSASLC6A9LTB4RPRMT6PPARD | |
| SCHEMBL9255816 | 0.74 | LTB4R (0.43) | CTSASLC6A9RXRARXRBLTB4R | |
| SCHEMBL9258419 | 0.74 | P2RX3 (0.44) | CTSASLC6A9LTB4RPRMT6PPARD | |
| SCHEMBL9258359 | 0.73 | F9 (0.54) | RXRARXRB | |
| SCHEMBL30963937 | 0.72 | RXRA (0.51) | CTSARXRARXRBPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |