Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | DGKA | P23743 | 4/20 | 0.38 |
| ▸ | DGKZ | Q13574 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253427 | 0.94 | OPRD1 (0.42) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL9253418 | 0.77 | OPRL1 (0.40) | DGKADGKZCYP19A1OPRD1OPRM1 | |
| SCHEMBL9256528 | 0.76 | DGKA (0.34) | DGKADGKZOPRD1OPRM1OPRK1 | |
| SCHEMBL7427594 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL21831659 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL25328640 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL7430109 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL21831126 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL7427589 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 | |
| SCHEMBL25327760 | 0.73 | SIGMAR1 (0.54) | SIGMAR1DGKADGKZDPP8OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |