Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256528 | 0.92 | DGKA (0.34) | OPRL1OPRD1OPRM1OPRK1DGKA | |
| SCHEMBL9252941 | 0.86 | OPRD1 (0.48) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL9253427 | 0.84 | OPRD1 (0.42) | OPRL1OPRD1OPRM1OPRK1DGKA | |
| SCHEMBL9256532 | 0.77 | SIGMAR1 (0.38) | OPRL1OPRD1OPRM1OPRK1DGKA | |
| SCHEMBL10504492 | 0.65 | OPRK1 (0.49) | OPRL1OPRD1OPRM1OPRK1IDO1 | |
| SCHEMBL4148340 | 0.64 | SLC6A9 (0.77) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL4139479 | 0.64 | SLC6A9 (0.77) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL4139483 | 0.64 | SLC6A9 (0.77) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL4139475 | 0.64 | SLC6A9 (0.77) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL9256147 | 0.64 | OPRM1 (0.59) | OPRL1OPRD1OPRM1OPRK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |