Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCOLN2 | Q8IZK6 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253418 | 0.92 | OPRL1 (0.40) | DGKADGKZOPRD1OPRM1OPRK1 | |
| SCHEMBL9252941 | 0.78 | OPRD1 (0.48) | OPRD1OPRM1OPRK1OPRL1CYP3A4 | |
| SCHEMBL9253427 | 0.77 | OPRD1 (0.42) | DGKADGKZOPRD1OPRM1OPRK1 | |
| SCHEMBL9256532 | 0.76 | SIGMAR1 (0.38) | DGKADGKZOPRD1OPRM1OPRK1 | |
| SCHEMBL9253761 | 0.59 | OPRM1 (0.54) | OPRD1OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL1047912 | 0.57 | CES2 (0.44) | MEN1ALDH1A1CYP3A4MAPTCYP2C9 | |
| Ethylene SCHEMBL27820289 | 0.57 | GABRA1 (0.46) | MEN1ALDH1A1CYP3A4MAPTCYP2C9 | |
| SCHEMBL15903486 | 0.57 | ACHE (0.43) | MEN1ALDH1A1CYP3A4MAPTCYP2C9 | |
| SCHEMBL31852251 | 0.57 | GABRA1 (0.50) | MEN1ALDH1A1CYP3A4MAPTCYP2C9 | |
| SCHEMBL84442 | 0.57 | GABRA1 (0.50) | MEN1ALDH1A1CYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |