Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257188 | 0.91 | NQO2 (0.38) | F10PRSS1ITGB3ITGA2BCHRNA7 | |
| SCHEMBL9251260 | 0.90 | F10 (0.36) | P4HTMF10PRSS1SMN1; SMN2FYN | |
| SCHEMBL9247213 | 0.83 | ITGB3 (0.39) | PRSS1ITGB3ITGA2B | |
| SCHEMBL9259191 | 0.81 | NQO2 (0.38) | SMN1; SMN2ITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL9250761 | 0.79 | F2 (0.40) | F10PRSS1ITGB3ITGA2B | |
| SCHEMBL9255129 | 0.79 | ITGB3 (0.36) | PRSS1ITGB3ITGA2B | |
| SCHEMBL9248487 | 0.76 | AGER (0.38) | SMN1; SMN2ITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL9254897 | 0.74 | ITGB3 (0.45) | PRSS1ITGB3ITGA2B | |
| SCHEMBL9251266 | 0.74 | ITGB3 (0.40) | PRSS1ITGB3ITGA2B | |
| SCHEMBL9280389 | 0.73 | ITGB3 (0.35) | F10PRSS1ITGB3ITGA2BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |