Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 4/20 | 0.33 |
| ▸ | FNTB | P49356 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265911 | 0.87 | F2 (0.39) | KDM4EALDH1A1SMN1; SMN2F2 | |
| SCHEMBL9257785 | 0.78 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9261314 | 0.78 | PTGIR (0.42) | MAPTGABBR2GABBR1KDM4ERECQL | |
| SCHEMBL9259379 | 0.77 | CYP1A2 (0.42) | — | |
| SCHEMBL9261597 | 0.76 | GABBR2 (0.51) | MAPTGABBR2GABBR1KDM4EALDH1A1 | |
| SCHEMBL7655013 | 0.76 | MAPT (0.55) | MAPTGABBR2GABBR1KDM4EALDH1A1 | |
| SCHEMBL5961389 | 0.76 | KDM4E (0.44) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9265904 | 0.75 | CTSB (0.37) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9256503 | 0.73 | MAPT (0.41) | MAPTGABBR2GABBR1KDM4EALDH1A1 | |
| Methyl Alcohol SCHEMBL9254484 | 0.71 | MAPT (0.45) | MAPTGABBR2GABBR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |